Decoding the Genomic Landscape of Disease

The Vujković Lab at the University of Pennsylvania integrates advanced genomics, computational biology, and clinical epidemiology to understand the complex interplay between genetic factors and metabolic diseases. Over the past decade, we have witnessed remarkable advances in our ability to identify genetic risk factors, yet the translation of these discoveries into clinical applications remains challenging.

Our Vision

We are bridging the gap between genetic discovery and precision medicine by developing innovative approaches to understand how genetic variants interact with modifiable factors to influence disease risk and progression. Our mission is to transform genomic insights into actionable clinical strategies for prevention, early intervention, and treatment of obesity-related conditions, particularly non-alcoholic fatty liver disease, cirrhosis, and liver cancer.

Our Approach

Using large-scale, long-term studies and cutting-edge computational methods, we:

Identify genetic risk factors for metabolic diseases
Quantify how lifestyle and clinical factors modify genetic predisposition
Develop personalized risk assessment tools

Join Our Team

We are always seeking talented and motivated individuals to join our collaborative research environment. We welcome inquiries from prospective graduate students, postdoctoral fellows, and research specialists with backgrounds in genomics, bioinformatics, epidemiology, or related fields.

The Vujković Lab is part of the Department of Medicine at the Perelman School of Medicine, University of Pennsylvania, with affiliations to the Penn Center for Nutritional Science and Medicine, Penn Center for Molecular Studies in Digestive and Liver Diseases, and Penn Institute for Biomedical Informatics. Our research is conducted in collaboration with the Million Veteran Program at the US Department of Veteran Affairs.